PD25 - Diagnostic specificity of symptoms seen in Double Blind Placebo Control Food Challenges (DBPCFCs). Do subjective symptoms lead to false positive test results and overdiagnosis?

Background The double-blind placebo-controlled food challenge (DBPCFC) is considered to be the gold standard for diagnosing food allergy in children. During the DBPCFC, both objective and subjective symptoms are observed. Although subjective symptoms are thought to be less specific than objective symptoms, it is not known whether objective symptoms have a stronger association with a true positive result than subjective symptoms.